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F6796
Sigma
Anti-Fibroblast Growth Factor Receptor-2, Extracellular antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
| Synonym: | Anti-FGFR-2 |
| MDL number: | MFCD02096345 |
Description
| Immunogen | synthetic peptide corresponding to amino acids 362-374 of the extracellular region of human FGFR-2 (Bek). |
| Preparation Note | Affinity isolated on a peptide-agarose column. |
| Specificity | The antibody detects human FGFR-2 (bek) in extracts of transfected cells. |
| Physical form | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide |
Properties
| antibody form | affinity isolated antibody |
| clone | (polyclonal) |
| form | buffered aqueous solution |
| mol wt | antigen mol wt 115-125 kDa |
| species reactivity | human |
| application(s) | immunoblotting: 1:2,000 using extract of FGFR-2 transiently transfected cells |
| immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1,000 using trypsin-digested, human and animal tissue sections | |
| immunoprecipitation: 1:1,000 using extract of FGFR-2 transiently transfected cells | |
| Gene Information | human ... FGFR2(2263) |
| shipped in | dry ice |
| storage temp. | −20°C |
Safety
| WGK Germany | 2 |
References
| reference | Jing, X., et al., Fibroblast growth factor 23 reduces expression of type IIa Na+/Pi co-transporter by signaling through a receptor functionally distinct from the known FGFRs in opossum kidney cells. Genes Cells 10, 489-502, (2005) Abstract |
| Kuslak, S., et al., The mouse seminal vesicle shape mutation is allelic with Fgfr2. Development 134, 557-565, (2007) Abstract |
